7.1 Protein Function

Proteins are one of the most abundant organic molecules in living systems. About half of the dry weight of a cell is protein. Proteins have the most diverse range of functions of all the macromolecules. They are the main molecules that carry out the functions of the cell.

The major reason that proteins are so varied in their function is due to their ability to bind other molecules. Various proteins can bind other proteins, DNA, RNA, lipids, carbohydrates, ions, or small molecules. Proteins are specific in their binding abilities; meaning certain proteins can only bind to certain molecules. The generic name for a molecule that a protein binds is ligand, and the place on the protein where it binds is the binding site.

The ability to specifically bind other molecules is a characteristic of a protein’s shape.

Three ways to represent the three-dimensional structure of a protein
Three of the many ways to represent the three-dimensional structure of a protein. Left: all-atom representation. Center: ribbon diagram, showing regions of secondary structure (alpha-helix in purple; beta-sheet in yellow). Right: Surface representation colored by type of amino acid (nonpolar white, polar green, acidic red, basic blue). (Protein views by Opabinia regalis is used under a Creative Commons Attribution-ShareAlike license).

Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, communication, or defense; or they may be toxins or enzymes. Each cell in a living system contains thousands of different proteins, each with a unique function. Their structures, like their functions, vary greatly, but they are all amino acid polymers arranged in a linear sequence.

 

Proteins are synthesized by ribosomes, which attach amino acids together to form a polypeptide, which folds into its three-dimensional shape.


Text adapted from OpenStax Biology 2e and used under a Creative Commons Attribution License 4.0.
Access for free at https://openstax.org/books/biology-2e/pages/1-introduction
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